St. George's Basilica originated as the second church at Prague Castle. Only the foundations of the building, founded about 920 by Prince Vratislav I have been preserved. When the convent for Benedictine nuns was founded in 973 the church was enlarged and reconstructed.

The interior of the basilica is Romanesque, austere and monumental. The tombs of members of the Premyslid dynasty of princes are situated in the main nave.
The southern side of the chancel is adjoined by St. Ludmila's Chapel. The convent has a simple and soberly decorated Early Baroque facade. From the eastern branch of the cloister access can be gained to St. Anne's Chapel in the convent.